1/11/2023
ΚΟΚΚΙΝΟ ΚΡΕΑΣ και ΦΛΕΓΜΟΝΗ
|
Η φλεγμονή αποτελεί βασικό παράγοντα τόσο στην εμφάνιση όσο και στην εξέλιξη πολλών χρόνιων και αυτοάνοσων παθήσεων. Δείτε την σχετική ανάρτηση με τίτλο "Φλεγμονή".
Το κόκκινο κρέας έχει αναγνωριστεί ως "προφλεγμονώδες", δηλαδή π ρ ο ά γ ε ι την φλεγμονή (1). Πολλές ακόμα επιστημονικές μελέτες αναφέρουν την φλεγμονή από το κόκκινο κρέας. Ενδεικτικά, ακολουθούν 19 εξ'αυτών (2-20). Συνεπώς, η αντικατάσταση του κόκκινου κρέατος από τα όσπρια προσφέρει σημαντικά οφέλη στον οργανισμό διότι τα όσπρια : - όχι μόνο δεν είναι π ρ ο φλεγμονώδη αλλά, - απεναντίας, είναι α ν τ ι φλεγμονώδη. |
ΚΟΚΚΙΝΟ ΚΡΕΑΣ και ΦΛΕΓΜΟΝΗ
|
|
Το κόκκινο κρέας έχει αναγνωριστεί ως "προφλεγμονώδες", δηλαδή π ρ ο ά γ ε ι την φλεγμονή (1).
Το κόκκινο κρέας περιέχει υψηλά επίπεδα χολίνης, η οποία είναι πρόδρομη ένωση του φλεγμονώδους μεταβολίτη TMAO (trimethylamine-N-oxide : τριμεθυλαμίνη-Ν-οξείδιο). O ΤΜΑΟ προέρχεται τόσο από την χολίνη όσο και από την καρνιτίνη που υπάρχουν στο κόκκινο κρέας. Σε ανθρώπους με ρευματοειδή αρθρίτιδα (χρόνια φλεγμονώδης αυτοάνοση διαταραχή), μία επιστημονική ομάδα προτείνει αντιφλεγμονώδη διατροφή η οποία αποφεύγει τα φλεγμονώδη τρόφιμα, όπως το κόκκινο κρέας (1) |
Κόκκινο κρέας: Έχει αναγνωριστεί ως "προφλεγμονώδες", δηλαδή προάγει την φλεγμονή
|
Παραπομπή:
1. Bustamante MF, Agustín-Perez M, Cedola F, Coras R, Narasimhan R, Golshan S, Guma M. Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis. Contemp Clin Trials Commun. 2020 Jan 21;17:100524. doi: 10.1016/j.conctc.2020.100524. PMID: 32025586; PMCID: PMC6997513.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997513/
2. Hosseinpour-Niazi S, Mirmiran P, Fallah-Ghohroudi A, Azizi F. Non-soya legume-based therapeutic lifestyle change diet reduces inflammatory status in diabetic patients: a randomised cross-over clinical trial. Br J Nutr. 2015 Jul;114(2):213-9. doi: 10.1017/S0007114515001725. Epub 2015 Jun 16. PMID: 26077375.
https://pubmed.ncbi.nlm.nih.gov/26077375/
3. Hosseinpour-Niazi S, Mirmiran P, Hadaegh F, Daneshpour MS, Hedayati M, Azizi F. The effect of TCF7L2 polymorphisms on inflammatory markers after 16 weeks of legume-based dietary approach to stop hypertension (DASH) diet versus a standard DASH diet: a randomised controlled trial. Nutr Metab (Lond). 2022 May 18;19(1):35. doi: 10.1186/s12986-022-00671-7. PMID: 35585604; PMCID: PMC9118794.
https://pubmed.ncbi.nlm.nih.gov/35585604/
4. University of Sydney, Meat eating link to inflammation, worse gut health and MS 28 January 2022
https://www.sydney.edu.au/news-opinion/news/2022/01/28/meat-eating-linked-to-inflammation-worse-gut-health-and-ms.html
5. Anti Inflammatory Diet, Johns Hopkins University
https://www.hopkinsmedicine.org/health/wellness-and-prevention/anti-inflammatory-diet
6. Oregon State University, Foods That Fight Inflammation and Chronic Disease, Stephanie Polizzi EM 9382 | February 2023,
https://extension.oregonstate.edu/catalog/pub/em-9382-foods-fight-inflammation-chronic-disease
7. Zhuang YY, Zheng HY, Lan H, Li HW. [Study on the correlation between dietary N-glycolylneuraminic acid intake and chronic inflammation state of body]. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Jun 6;54(6):668-672. Chinese. doi: 10.3760/cma.j.cn112150-20191021-00802. PMID: 32842284.
https://pubmed.ncbi.nlm.nih.gov/32842284/
8. Montonen, J., Boeing, H., Fritsche, A. et al. Consumption of red meat and whole-grain bread in relation to biomarkers of obesity, inflammation, glucose metabolism and oxidative stress. Eur J Nutr 52, 337–345 (2013). https://doi.org/10.1007/s00394-012-0340-6
https://link.springer.com/article/10.1007/s00394-012-0340-6
9. Ley SH, Sun Q, Willett WC, Eliassen AH, Wu K, Pan A, Grodstein F, Hu FB. Associations between red meat intake and biomarkers of inflammation and glucose metabolism in women. Am J Clin Nutr. 2014 Feb;99(2):352-60. doi: 10.3945/ajcn.113.075663. Epub 2013 Nov 27. PMID: 24284436; PMCID: PMC3893727.
https://pubmed.ncbi.nlm.nih.gov/24284436/
10. Mazidi, M., Kengne, A., George, E., & Siervo, M. (2021). The association of red meat intake with inflammation and circulating intermediate biomarkers of type 2 diabetes is mediated by central adiposity. British Journal of Nutrition, 125(9), 1043-1050. doi:10.1017/S0007114519002149
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/association-of-red-meat-intake-with-inflammation-and-circulating-intermediate-biomarkers-of-type-2-diabetes-is-mediated-by-central-adiposity/B23304E3D583D622EFFB32919E8C53A7
11. Khuu, B., Pierce, J., & Wu, T. (2019). Red Meat and Inflammation and A1c in Breast Cancer Women (P05-038-19). Current developments in nutrition, 3(Suppl 1). Retrieved from https://escholarship.org/uc/item/3hk6b5gm
https://escholarship.org/uc/item/3hk6b5gm
12. Original Research, Unprocessed red meat intakes are associated with increased inflammation, triglycerides and HDL cholesterol in past smokers
Tianying Wu, Samantha Sonoda, Hongxia Liu
https://onlinelibrary.wiley.com/doi/10.1111/1747-0080.12555
13. Papier K, Hartman L, Tong TYN, Key TJ, Knuppel A. Higher Meat Intake Is Associated with Higher Inflammatory Markers, Mostly Due to Adiposity: Results from UK Biobank. J Nutr. 2022 Jan 11;152(1):183-189. doi: 10.1093/jn/nxab314. PMID: 34587250; PMCID: PMC8754571.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754571/
14. Harvard Health, Foods that fight inflammation November 16, 2021,
https://www.health.harvard.edu/staying-healthy/foods-that-fight-inflammation
15. Harvard Health, Diet Review: Anti-Inflammatory Diet, October 2021
https://www.hsph.harvard.edu/nutritionsource/healthy-weight/diet-reviews/anti-inflammatory-diet/
16. Kim E, Lee JS, Kim E, Lee MA, Fonteh AN, Kwong M, Cho YH, Lee UJ, Yang M. Metabolic Evidence Rather Than Amounts of Red or Processed Meat as a Risk on Korean Colorectal Cancer. Metabolites. 2021 Jul 16;11(7):462. doi: 10.3390/metabo11070462. PMID: 34357356; PMCID: PMC8303103.
https://pubmed.ncbi.nlm.nih.gov/34357356/
17. Yu Z, Malik VS, Keum N, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS, Bao Y. Associations between nut consumption and inflammatory biomarkers. Am J Clin Nutr. 2016 Sep;104(3):722-8. doi: 10.3945/ajcn.116.134205. Epub 2016 Jul 27. PMID: 27465378; PMCID: PMC4997300.
https://pubmed.ncbi.nlm.nih.gov/27465378/
18. Montonen J, Boeing H, Fritsche A, Schleicher E, Joost HG, Schulze MB, Steffen A, Pischon T. Consumption of red meat and whole-grain bread in relation to biomarkers of obesity, inflammation, glucose metabolism and oxidative stress. Eur J Nutr. 2013 Feb;52(1):337-45. doi: 10.1007/s00394-012-0340-6. Epub 2012 Mar 18. PMID: 22426755; PMCID: PMC3549403.
https://pubmed.ncbi.nlm.nih.gov/22426755/
19. Azadbakht L, Esmaillzadeh A. Red meat intake is associated with metabolic syndrome and the plasma C-reactive protein concentration in women. J Nutr. 2009 Feb;139(2):335-9. doi: 10.3945/jn.108.096297. Epub 2008 Dec 11. PMID: 19074209.
https://www.sciencedirect.com/science/article/pii/S0022316622066512
20. Shiraseb, F., Hosseininasab, D., Mirzababaei, A., Bagheri, R., Wong, A., Suzuki, K., & Mirzaei, K. (2022). Red, white, and processed meat consumption related to inflammatory and metabolic biomarkers among overweight and obese women. Frontiers in Nutrition, 9, Article 1015566. https://doi.org/10.3389/fnut.2022.1015566
https://waseda.elsevierpure.com/en/publications/red-white-and-processed-meat-consumption-related-to-inflammatory-
1. Bustamante MF, Agustín-Perez M, Cedola F, Coras R, Narasimhan R, Golshan S, Guma M. Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis. Contemp Clin Trials Commun. 2020 Jan 21;17:100524. doi: 10.1016/j.conctc.2020.100524. PMID: 32025586; PMCID: PMC6997513.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997513/
2. Hosseinpour-Niazi S, Mirmiran P, Fallah-Ghohroudi A, Azizi F. Non-soya legume-based therapeutic lifestyle change diet reduces inflammatory status in diabetic patients: a randomised cross-over clinical trial. Br J Nutr. 2015 Jul;114(2):213-9. doi: 10.1017/S0007114515001725. Epub 2015 Jun 16. PMID: 26077375.
https://pubmed.ncbi.nlm.nih.gov/26077375/
3. Hosseinpour-Niazi S, Mirmiran P, Hadaegh F, Daneshpour MS, Hedayati M, Azizi F. The effect of TCF7L2 polymorphisms on inflammatory markers after 16 weeks of legume-based dietary approach to stop hypertension (DASH) diet versus a standard DASH diet: a randomised controlled trial. Nutr Metab (Lond). 2022 May 18;19(1):35. doi: 10.1186/s12986-022-00671-7. PMID: 35585604; PMCID: PMC9118794.
https://pubmed.ncbi.nlm.nih.gov/35585604/
4. University of Sydney, Meat eating link to inflammation, worse gut health and MS 28 January 2022
https://www.sydney.edu.au/news-opinion/news/2022/01/28/meat-eating-linked-to-inflammation-worse-gut-health-and-ms.html
5. Anti Inflammatory Diet, Johns Hopkins University
https://www.hopkinsmedicine.org/health/wellness-and-prevention/anti-inflammatory-diet
6. Oregon State University, Foods That Fight Inflammation and Chronic Disease, Stephanie Polizzi EM 9382 | February 2023,
https://extension.oregonstate.edu/catalog/pub/em-9382-foods-fight-inflammation-chronic-disease
7. Zhuang YY, Zheng HY, Lan H, Li HW. [Study on the correlation between dietary N-glycolylneuraminic acid intake and chronic inflammation state of body]. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Jun 6;54(6):668-672. Chinese. doi: 10.3760/cma.j.cn112150-20191021-00802. PMID: 32842284.
https://pubmed.ncbi.nlm.nih.gov/32842284/
8. Montonen, J., Boeing, H., Fritsche, A. et al. Consumption of red meat and whole-grain bread in relation to biomarkers of obesity, inflammation, glucose metabolism and oxidative stress. Eur J Nutr 52, 337–345 (2013). https://doi.org/10.1007/s00394-012-0340-6
https://link.springer.com/article/10.1007/s00394-012-0340-6
9. Ley SH, Sun Q, Willett WC, Eliassen AH, Wu K, Pan A, Grodstein F, Hu FB. Associations between red meat intake and biomarkers of inflammation and glucose metabolism in women. Am J Clin Nutr. 2014 Feb;99(2):352-60. doi: 10.3945/ajcn.113.075663. Epub 2013 Nov 27. PMID: 24284436; PMCID: PMC3893727.
https://pubmed.ncbi.nlm.nih.gov/24284436/
10. Mazidi, M., Kengne, A., George, E., & Siervo, M. (2021). The association of red meat intake with inflammation and circulating intermediate biomarkers of type 2 diabetes is mediated by central adiposity. British Journal of Nutrition, 125(9), 1043-1050. doi:10.1017/S0007114519002149
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/association-of-red-meat-intake-with-inflammation-and-circulating-intermediate-biomarkers-of-type-2-diabetes-is-mediated-by-central-adiposity/B23304E3D583D622EFFB32919E8C53A7
11. Khuu, B., Pierce, J., & Wu, T. (2019). Red Meat and Inflammation and A1c in Breast Cancer Women (P05-038-19). Current developments in nutrition, 3(Suppl 1). Retrieved from https://escholarship.org/uc/item/3hk6b5gm
https://escholarship.org/uc/item/3hk6b5gm
12. Original Research, Unprocessed red meat intakes are associated with increased inflammation, triglycerides and HDL cholesterol in past smokers
Tianying Wu, Samantha Sonoda, Hongxia Liu
https://onlinelibrary.wiley.com/doi/10.1111/1747-0080.12555
13. Papier K, Hartman L, Tong TYN, Key TJ, Knuppel A. Higher Meat Intake Is Associated with Higher Inflammatory Markers, Mostly Due to Adiposity: Results from UK Biobank. J Nutr. 2022 Jan 11;152(1):183-189. doi: 10.1093/jn/nxab314. PMID: 34587250; PMCID: PMC8754571.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754571/
14. Harvard Health, Foods that fight inflammation November 16, 2021,
https://www.health.harvard.edu/staying-healthy/foods-that-fight-inflammation
15. Harvard Health, Diet Review: Anti-Inflammatory Diet, October 2021
https://www.hsph.harvard.edu/nutritionsource/healthy-weight/diet-reviews/anti-inflammatory-diet/
16. Kim E, Lee JS, Kim E, Lee MA, Fonteh AN, Kwong M, Cho YH, Lee UJ, Yang M. Metabolic Evidence Rather Than Amounts of Red or Processed Meat as a Risk on Korean Colorectal Cancer. Metabolites. 2021 Jul 16;11(7):462. doi: 10.3390/metabo11070462. PMID: 34357356; PMCID: PMC8303103.
https://pubmed.ncbi.nlm.nih.gov/34357356/
17. Yu Z, Malik VS, Keum N, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS, Bao Y. Associations between nut consumption and inflammatory biomarkers. Am J Clin Nutr. 2016 Sep;104(3):722-8. doi: 10.3945/ajcn.116.134205. Epub 2016 Jul 27. PMID: 27465378; PMCID: PMC4997300.
https://pubmed.ncbi.nlm.nih.gov/27465378/
18. Montonen J, Boeing H, Fritsche A, Schleicher E, Joost HG, Schulze MB, Steffen A, Pischon T. Consumption of red meat and whole-grain bread in relation to biomarkers of obesity, inflammation, glucose metabolism and oxidative stress. Eur J Nutr. 2013 Feb;52(1):337-45. doi: 10.1007/s00394-012-0340-6. Epub 2012 Mar 18. PMID: 22426755; PMCID: PMC3549403.
https://pubmed.ncbi.nlm.nih.gov/22426755/
19. Azadbakht L, Esmaillzadeh A. Red meat intake is associated with metabolic syndrome and the plasma C-reactive protein concentration in women. J Nutr. 2009 Feb;139(2):335-9. doi: 10.3945/jn.108.096297. Epub 2008 Dec 11. PMID: 19074209.
https://www.sciencedirect.com/science/article/pii/S0022316622066512
20. Shiraseb, F., Hosseininasab, D., Mirzababaei, A., Bagheri, R., Wong, A., Suzuki, K., & Mirzaei, K. (2022). Red, white, and processed meat consumption related to inflammatory and metabolic biomarkers among overweight and obese women. Frontiers in Nutrition, 9, Article 1015566. https://doi.org/10.3389/fnut.2022.1015566
https://waseda.elsevierpure.com/en/publications/red-white-and-processed-meat-consumption-related-to-inflammatory-
